When first diagnosed with ALS, one of the first questions people ask is whether it is OK to continue exercising. A recently completed ALS Association funded study by Dr. Nicholas Maragakis of Johns Hopkins University and team set out to help answer this common question by exploring the possible benefits of exercise for people living with ALS. They found that stretching, resistance, and endurance exercise are all safe and tolerable to perform with a specified program. Exercise did not worsen outcomes related to ALS disease. The article was published in journal Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration.
This year’s annual Society for Neuroscience (SfN) Meeting in Washington, D.C., was a huge gathering of over 30,000 attendees from 80 countries all dedicated to advancing neuroscience. The ALS Association was one of 534 exhibitors and promoted our global TREAT ALS research program. We met people and answer their questions about ALS. Multiple presentation sessions and posters were dedicated to ALS and many of our funded researchers attended to present and discuss their latest findings. Here are some highlights of the many top ALS scientists that we fund who generously shared with us the progress they have recently made.
Dr. Pierre Drapeau (pictured above) and team of Université de Montréal recently published an important paper in JCI Insight showing how basic animal models are used to identify ALS potential therapeutics. They found that pimozide, a neuroleptic drug, was the most potent in impacting animal model mobility. A short clinical trial was then conducted in sporadic ALS patients, which demonstrated that the drug hit its target and safe at a specific dose. Evidence from these studies paved the way for the current randomized pimozide phase II clinical trial that began enrollment this month in Canada. We are proud to support these studies through the Lawrence and Isabel Barnett Drug Development Program, and your donations.
First there was Black Friday… Then Cyber Monday…
By now, you’ve probably heard of #GivingTuesday – the global day of giving back! And while it’s a great day to raise money for ALS, #GivingTuesday is trending on all social networks, making it the best time to share your ALS story. We’ll share your stories on our social channels in the hopes of inspiring others to join us in the fight against ALS.
Are you ready for some Cyber Monday deals?! Turn those deals into support for people living with ALS and their families by shopping through AmazonSmile.
By Stephen Winthrop
If you ever run into me, you’ll notice that I am wearing a button that says, “I have ALS. Ask me about it.” I love this button because of the conversations it creates with people who want to learn more about ALS and my own journey. Now, I’d like to have an important conversation with you.
We bring the ALS community together to speak with one voice to increase awareness, advocate for research funding, and educate legislators – impacting thousands of people with ALS and their families. This advances our mission to discover treatments and a cure, and to serve, advocate for, and empower people living with ALS to live their lives to the fullest.